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Not all medications and nutrients are small enough to get absorbed or need breakdown via gastric enzymes for activation for the sublingual route, but whenever possible there is a benefit to using this route as it bypasses potential damage/absorption issues in the GI tract

This means that as we age, our bodies become less efficient at absorbing B12, making deficiency more common among the elderly

Though it has only a single mechanism, the medication is provided as an oral formulation that has the potential to increase adherence and patient access to the medication

Lactoferrin was compared to ferrous sulfate and was found to be more effective at raising serum iron, hemoglobin, and ferritin levels, while being better tolerated, leading to less GI distress

The 2026 Prohibited List took effect on 1 January 2026