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Subsequently, the NLRP3 complex assembles and proceeds to convert pro-IL-1 into its active form, IL-1, intensifying the inflammatory response (51)

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These compounds are produced by the cells of various organisms as part of their innate immunity, and they provide protection against various pathogens (bacteria, viruses, and fungi), as well as acting as mediators of immune responses (Lei et al

The MFC group demonstrated a therapeutic response with ameliorated dermatitis symptoms, while the SHFKO group showed alleviated hyperkeratosis, reduced epidermal hypertrophy, and attenuated inflammatory cell infiltration