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IARC monographs on the evaluation of the carcinogenic risk of chemicals to humans, vol 32

Cigarette smoke exposure HBE cells were exposed to mainstream smoke from 3R4F University of Kentucky reference cigarettes (Lexington, KY) using a VC-10 Smoking Robot (Vitrocell, Waldkirch, Germany) in accordance with ISO 3308 standards (puff duration 2 s, hold time 0 s, exhaust time 8 s, puff volume 35 mL, frequency 60 s, 6 puffs per cigarette)

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This is especially evident in African regions such as Eastern Sub-Saharan Africa, Western Sub-Saharan Africa, and Central Sub-Saharan Africa, where the contribution of population growth to DALYs is 236.07, 142.57, and 154.44%, respectively, while the contribution of population aging to DALYs is negative: 20.78, 13.77%, and 12.65%

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For example, if participants naturally introduced views on the harms of IQOS, their responses were probed in full by asking questions such as why do you say that? and where did you get this information from?