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Iron chelation may be utilized to artificially trigger HIF1-mediated pro-inflammatory and glycolytic pathways in host immune cells during Mtb infection

A randomized controlled trial revealed that 2 weeks of EA (PC 6 and GV 26) treatment improved cognitive recovery among 40 patients with mild TBI (Jia et al., 2023)

On the other hand, inducers increase P-450 activity by increasing enzyme production, or, in the case of CYP2E1, preventing degradation in the proteasome