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For people with no neurological involvement Initially administer hydroxocobalamin 1 mg intramuscularly three times a week for 2 weeks, then administer hydroxocobalamin 1 mg intramuscularly every 23 months for life

12 , 13 Individuals with vitamin B12 deficiency may be at greater risk of patient safety incidents in primary care as they often describe suboptimal communication, lack of dignity and respect, and feelings that healthcare professionals lack the knowledge, skills, and attitudes to adequately treat their condition

DOI: 10.1111/j.1365-2265.2009.03588.x 28

In this article, we will explore some of the various theories that are currently in circulation, which outline the cause as: Excessive production of porphyrin by skin bacteria stimulated by B12 A cobalt allergy Relative deficiency of vitamin B12 cofactors A detoxification reaction Vitamin B12 Acne The Work of Skin Bacteria