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With regard to the molecular toxic mechanisms of tobacco, oxidative stress or inflammasome activation as well as a chronic activation of aryl hydrocarbon receptor signaling can contribute to premature aging and the development of neoplasms by affecting metabolism, extracellular matrix remodeling, inflammation, pigmentation, DNA repair, and apoptosis 10

Lancet Neurol 2002, 1: 251257

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But its new conservative coalition government, which took power this week, has now promised to scrap a so-called generational smoking ban that would have stopped sales of tobacco to anyone born after 2008.