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Early-stage trials (I) are designed to test safety and find the appropriate dosage of the treatment, whereas later stage trials (II and III) are designed to assess efficacy and gather the information needed for approval by the FDA and other regulatory agencies

About 5-10% of people with coeliac disease do not have a positive EMA test

Enhanced fatty acid synthesis leads to subset imbalance and IFN- Overproduction in T helper 1 cells

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