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Safety of N -acetylcysteine at high doses in chronic respiratory diseases: a review

Ergothioneine is taken up by endothelial cells via SLC22A4 (Reference Li, Yang and Sit88) , where it has been demonstrated to limit reactive oxygen species production and damage from a variety of insults, including hyperglycaemia, through multiple mechanisms (Reference Li, Yang and Sit88,Reference DOnofrio, Servillo and Giovane89)

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If left unchecked, insulin resistance often leads to the development of metabolic syndrome, type 2 diabetes, liver disease, and cardiac disease

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