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But in some situations, I acknowledge it can be useful

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HK2 kinase assays were conducted in a mixed system by adding 50 ng of purified, active human HK2 to a kinase buffer containing 5 g of purified Flag-RIPK1

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However, in conditions when the protective checkpoints are blocked, RIPK1 induces apoptosis and/or necroptosis through its kinase activity 11,12,13

It depends on the specific treatment goals and the type of peptide used