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Here we have found a potent antioxidant moiety Scopoletin (Sp), a common derivative in most of the nootropic herbs, with robust neuroprotective ability

In conclusion, these findings demonstrate that a clinical intervention for 3-months with oral L-GSH in individuals with T2DM can decrease levels oxidized GSH, while maintaining levels of reduced GSH and overall reducing the extent of oxidative stress

Data extraction and Quality assessment The data in the included studies were extracted by two investigators independently using the same Data Extraction Form

PMID 14641005

However, like in breast cancer, the clinical application of rhamnetin faces challenges due to its poor solubility and rapid metabolism

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