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(55) found that in a mouse model of corneal alkali injury, the expression of ROS was upregulated, oxidative stress increased, the expression of the gene Ptgs2, a key marker of ferroptosis, was elevated, the level of the lipid peroxidation product 4-hydroxynonenal (4-HNE) increased, and the level of the ferroptosis regulator GPX4 decreased, with mitochondrial damage

Nurerk, P., Junden, S

With RI at 10 mg the induction was in GST activity

2019 Ahmed, N., Shamsabadi, A., Chudasama, V.* ACS Omega , 2019, 4, 22601-22612

PubMed PMID: 9879640

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