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Salicylic acid (0.5-2%) and retinoids work by dissolving the keratin plugs blocking hair follicles, but can actually worsen yeast conditions by increasing skin cell turnover that feeds Malassezia

Due to their high water content, structural similarity to natural tissues, and favorable biocompatibility, hydrogels are widely used in biomedical fields, particularly for drug delivery, facilitating controlled release and enhancing efficacy (198200)

Sci Rep 6:39628 Asurmendi P, Garca MJ, Pascual L, Barberis L (2015) Biocontrol of Listeria monocytogenes by lactic acid bacteria isolated from brewers grains used as feedstuff in Argentina

The target is to improve the overlay of the drug and release kinetics and prolong the shelf lifespan of the drug with fewer side effects

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In a previous work, our group discovered that the knockdown of genes involved in the TGFb signaling pathway protected LUHMES cells against aSyn-induced toxicity [10]