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Increased Energy Expenditure: GLP-1 RAs may activate sympathetic pathways in the hypothalamus (specifically the dorsomedial and ventromedial nuclei) that increase thermogenic activity in brown adipose tissue (BAT), contributing to increased energy expenditure and weight loss

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Appl In Vitro Toxicol 5:150166

This medium was then replaced with matched medium with glycine substituted for 0.4 mM 13 C 2 15 N 1 -glycine for 1 h before metabolite extraction

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These fibrillar adhesions are elongated structures that are associated with mature ECM fibrils and are considered to be late cell-matrix adhesions